IDENTIFICATION AND CHARACTERIZATION OF CALCIUM SPARKS IN CARDIOMYOCYTES DERIVED FROM HUMAN INDUCED PLURIPOTENT STEM CELLS.

Identification and characterization of calcium sparks in cardiomyocytes derived from human induced pluripotent stem cells.

INTRODUCTION: Ca2+ spark constitutes the elementary units of cardiac excitation-contraction (E-C) coupling in mature cardiomyocytes.Human induced pluripotent stem cell (hiPSC)-derived cardiomyocytes are known to have electrophysiological properties similar to mature adult cardiomyocytes.However, it is unclear if they share similar calcium handling

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Revealing multi-scale characteristics of ecosystem services supply and demand imbalance to enhance refined ecosystem management in China

Spatial heterogeneity in the supply and demand of ecosystem services across multi spatiotemporal scales facilitates the formulation of ecosystem management policies at diverse administrative levels.We mapped the five ecosystem services (ESs) in China, analyzed the spatiotemporal evolution of ESs supply and demand pattern from 2000 to 2020, revealed

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Sensitizing agents found in children and adolescents with recalcitrant atopic dermatitis: a cross-sectional study with a pediatric battery

Abstract Background Atopic dermatitis is the most common inflammatory skin disease in childhood and has an important impact on quality of life, especially severe cases or those that are recalcitrant to treatments.Sensitization to allergens with the potential for allergic contact dermatitis is a factor associated with Brush cases of recalcitrant ato

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Envisioning a Post-Conflict Tripoli: The Inclusive Urban Strategy and Action Plan for Bab Al-Tabbaneh and Jebel Mohsen

The Inclusive Urban Strategy and Action Plan is a study conducted by a multi-disciplinary international team focused on the post-conflict area of Tripoli, the second largest city of Lebanon.The project includes the neighbourhoods of Bab Al-Tabbaneh and Jebel Mohsen and the conflict zone in between where hostilities ended thanks to the Misc Connecto

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